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KMID : 0361020010440040423
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Korean Journal of Otolaryngology - Head and Neck Surgery
2001 Volume.44 No. 4 p.423 ~ p.426
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The role of salvage surgery in the treatment of irradiation-failed nasopharyngeal carcinoma
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이원상/Won Sang Lee
최재영/홍정표/조창현/김상엽/Jae Young Choi/Jung Pyo Hong/Chang Hyun Cho/Sang Yep Kim
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Abstract
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Background and Objectives: When nasopharyngeal carcinomas recur after radiotherapy, it becomes difficult to select further treatment modality. We reviewed surgical results of irradiation-failed nasopharyngeal carcinoma patients and investigated
the
role
of salvage surgery.
Materials and Methods: Surgical results of 10 cases of nasopharyngeal
carcinoma were investigated. All of them had a recurrent or residual
nasopharyngeal carcinoma after radiation therapy. The medical records of
these patients were reviewed retrospectively and the mean survival time
was calculated by Kaplan-Meier method. Results: The mean survival
time of the irradiation-failed nasopharyngeal carcinoma patients was 21.8
months. The survival times of early staged irradiation-failed tumor were
longer than that of the tumor in the advance stage. Among 3 patients
whose recurrent tumor stages were T1, two patients had the negative
resection margin and they lived without the disease. However, none of
the patients whose recurrent tumor stages were beyond T2(n=7) had the
negative resection margin and lived without the disease. Conclusion:
Surgical treatment was an useful treatment modality for improving the
survival time of early staged irradiation-failed nasopharyngeal carcinomas.
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KEYWORD
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